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Clinical Research

[ program | courses ]

All courses, faculty listings, and curricular and degree requirements described herein are subject to change or deletion without notice.

Program Director

Ravindra L. Mehta, MD, Professor of Clinical Medicine

Associate Program Director

J. Allen McCutchan, MD, MSc, Professor of Medicine (Active Emeritus )

Associated Faculty

Wael Al-Delaimy, MD, PhD, Professor and Division Chief, Department of Family Medicine and Public Health

Cheryl Anderson, PhD, MPH, MS, Professor and Interim Chair, Department of Family Medicine and Public Health

Maria “Happy” Araneta, MD, Professor, Department of Family Medicine and Public Health

John Bellettierre, PhD, Postdoctoral Fellow, Department of Family Medicine and Public Health

Richard Calvo, PhD, Research Epidemiologist, Scripps Mercy Hospital

Christina Chambers, PhD, MPH, Professor, Department of Pediatrics

Raphael Cuomo, PhD, MPH, CPH, FRSPH, Academic Coordinator, UC San Diego Extension

Colin Depp, PhD, Associate Professor, Department of Psychiatry

Jennifer J. Ford, MBA, Director, Conflict of Interest, Research Compliance and Integrity, Office of the Vice Chancellor for Research

Michael Hogarth, MD, Chief Clinical Research Information Officer, UC San Diego Health

Samantha Hurst, PhD, Clinical Professor, Department of Family Medicine and Public Health

Regent Laporte, DVM, MSc, PhD, Instructor, Clinical and Translational Research Institute

Anne Liljenstrand, PhD, Managing Director, The Bader Group

Etienne Macedo, MD, PhD, FASN, Assistant Professor, Department of Medicine, Division of Nephrology

Timothy Mackey, MAS, PhD, Director of Health Research/Policy, Associate Professor, Department of Anesthesiology

Sheldon Morris, MD, MPH, Assistant Clinical Professor of Medicine

James Murphy, MD, MS, Associate Professor, Department of Radiation Medicine and Applied Sciences

Lucila Ohno-Machado, MD, PhD, Professor, Department of Medicine

Hemal H. Patel, PhD, Professor, Department of Anesthesiology

Bernice Ruo, MD, MAS, FACP, Clinical Professor of Medicine, Department of Medicine

Andrew Sarkin, PhD, Director of Evaluation Research, Health Services Research, Department of Family Medicine and Public Health

Siddharth Singh, MD, MS, Assistant Professor, Department of Medicine, Division of Gastroenterology

Florin Vaida, PhD , Professor, Department of Family Medicine and Public Health, Division of Biostatistics and Bioinformatics

Michael G. Ziegler, MD, Professor, Department of Medicine

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Education and Training

Clinical research enhancement through supplemental training (crest) program.

 A career in clinical research increasingly requires high levels of preparation, training, and commitment similar to a career in laboratory-based research. While it is common for physicians/scientists to dedicate several years of focused effort to master the techniques and strategies required for productive careers in laboratory research, individuals embarking on a career in clinical investigation only recently have had a similar opportunity to develop their skills. This disparity is representative of the lack of structured training programs in clinical research. Recognizing this lack, the NIH has developed the K series of grants. These grants enhance development of investigators with specialized clinical and laboratory skills to use rigorous methods to address research questions with human populations. UCSD has incorporated these concepts in the design of the CREST program, under the direction of Ravindra Mehta, MD.

The main features of the program design are as follows.

Integrated Design for State-of-the-Art Training

Three characteristics common to successful training, whether it be in clinical or laboratory research, are: 1) training in research methods applicable to the area of investigation, 2) application of these methods to a state-of-the-art research question, and 3) collaboration with more experienced investigators. Well-trained laboratory researchers benefit from all three training components.  Research mentors provide a laboratory environment for instruction in research methods, which the trainee uses in a specific project while also interacting with other investigators in the field. Similarly, experienced clinician investigators utilize the clinic or hospital as a "laboratory" for their research. It is more difficult for clinical researchers to control the "laboratory" environment and provide comprehensive training. We have designed the CREST program to integrate the three components described above. The program requires the scholar to have an independent research project, provides the didactic and practical training required in the methods of clinical research, and creates an environment for the scholar to learn from a multidisciplinary faculty who provide individualized guidance for career development.

Broad-based Curriculum Encompassing Major Areas of Clinical Research

As clinical research is often multidisciplinary and multifaceted, a curriculum for instruction should be representative of the different components of clinical research, as defined by the NIH. Taking this into account we have incorporated all major elements of clinical research in the design of the curriculum. The curriculum is designed with courses given over two years.  It is comprised of eight modules which cover the principles of epidemiology, biostatistics, patient-oriented research (two modules each), health services/outcomes research, and data management/informatics (one module each). We believe that the CREST scholar must not only have a strong basis in academic medicine, but must understand the bioscience/biotechnology to be an effective researcher. Consequently, we include professional development seminars that are offered throughout the two years and focused on key elements including grant writing, scientific communication, research management and time management.

Components of CREST Program Curriculum

Each module is given over one academic quarter and is comprised of 10 weekly, 2-hour periods of instruction in the early evening. The format for instruction includes a combination of didactic lectures, group discussions, and hands-on computer-based training. Once-a-week evening classes allow the scholar to focus on his/her primary research and training project without disrupting clinical responsibilities during the major part of the work week. For individuals interested in completing the CREST curriculum in a shorter time period, a one year option is available. This requires both the first and second year courses be taken concurrently on two nights a week (Wednesday and Thursday)  e.g. year 1 course on Wednesday and year 2 course on Thursday. However, the sessions must begin with either the Winter session in January or Summer session in July.

Targeted Participants with Track System for Enrollment

The program is primarily directed towards postdoctoral candidates with a M.D. or Ph.D. degree interested in pursuing a career in clinical investigation or translational research. Potential applicants will have a primary research training focus either in basic science or in clinical research. Scholars are recruited from many departments and disciplines and range from graduate students working towards a Masters degree to individuals holding junior faculty appointments. Scholars differ in levels of prior training and experience in areas covered by the curriculum, in levels of commitment, and in interests. In order to accommodate the varying needs we have incorporated two mechanisms to permit flexibility while retaining the benefits of structured modular instruction. First, scholars spend the majority of their time working on their primary focus for training as a basic scientist or a clinician investigator. Second, scholars are able to select from two training tracks for participating in the CREST program to supplement their training. Participants are assessed on application to the program for their goals and needs for training in specific areas. For those with more limited goals, Track I involves a smaller number of modules. For example, fellows whose interest and training focuses on laboratory research may elect to take only the modules involving biostatistics, career development, and ethical and regulatory issues. Those who pursue Track II commit to the entire ten-module, two-year curriculum. Taking all ten modules is equivalent to approximately 20 credits hours. Track II scholars have the option to enroll in the UCSD Masters of Advanced Studies in Clinical Research anytime during the first year of training and can apply the CREST curriculum credits towards the Masters degree.

Career Development

A key feature of the program is that it addresses the continuum of learning experienced by the scholar. In addition to the curriculum, each scholar who enrolls in the MAS program is required to have an individual research project supervised by his or her primary research mentor. In addition, each scholar is paired with a CREST faculty member, who serves as a mentor to assist with their individual research project as well a  providing career guidance. The CREST faculty interacts with the primary research mentor to ensure that scholars have the appropriate support and protected time to pursue their goals. In order to assign a CREST mentor to each applicant we require the applicant to complete a pre-course assessment form that provides information on content knowledge, needs and learning styles. These instruments are repeated at periodic intervals to track each applicant's progress through the duration of the training program.

UCSD residents, fellows, faculty (including laboratory-based fellows) MUST apply through CREST and pay a discounted fee up to 20 credit units. If interested in earning the CREST certificate and/or transferring to the MAS degree program, you must apply for Track II; if interested in individual courses, you should apply for Track I . The cost for staff, residents and fellows is $340 per unit ($680 per two-unit course) and for faculty it is $450 per unit ($900 per two-unit course). The fee covers the costs for lectures and course materials including books. The fee after completing 20 units and/or transferring to MAS program is $886 PER UNIT ($1,772 per two-unit course)!

Non-UCSD folks (coming from industry or other academic institutions) must apply through MAS program and pay the regular course fee; i.e., $886 per unit ($1,772per two-unit course) plus the registration fee. Details of the Master’s Degree program and fees can be found at the MAS web site: https://clre.ucsd.edu .

Prospective Students

Intended audience:.

CREST is targeted to fellows, junior faculty, Pharm.D, faculty members, and research associates interested in receiving supplemental training in clinical and translational research. We accept researchers from all disciplines, particularly physicians enrolled in fellowship training or starting their academic career. CREST also accepts UCSD staff with prior experience in clinical medicine (e.g. clinical research nurses, research associates) as concurrent students.

Admissions:

Applicants must read and understand the descriptions and objectives of the courses, review the course start and end dates, and review the overall program goals. Applicants must also agree to commit to attending at least 70% of the classes for each course, and completing the majority of the homework.

To apply for CREST (Clinical Research Enhancement through Supplemental Training), candidates will need to complete and submit the online CREST Program application.

The following  must also be included: Required Supplemental Documents  For All Applicants:

  • Statement of Purpose : please explain your specific research interests and goals, your individual strengths and what makes you a good candidate for this program, why you want to be in the program, and how it will assist you in achieving your career goals.
  • Three Letters of Recommendation:   recommendation letters must come from the recommender not the applicant. Choose recommences who know your skills and abilities, and can speak to why you are a good candidate for the program.
  • Unofficial copies of academic records: if your educational background is not MD , a copy of all undergraduate and graduate courses work/transcripts must accompany your submission. You could upload it with your application or email it as attachment [email protected] or fax to 858-534-9168
  • Current resume or C.V.

Application procedures:

"track system" to permits flexibility and accommodate the varying needs:.

  • Take only selected Courses.
  • Track I will be placed on a waiting list (first come-first serve) until administering Track II (the certificate/degree students). Enrollment is based on space availability.                                   
  • Complete CREST curriculum and earn  Advanced Certificate in Clinical Research
  • Transfer to the  Masters of Advanced Studies in Clinical Research Degree Program during the first year of training and apply the CREST curriculum credits towards the Masters degree.
  • Could enter in (January) or summer (July) quarter.

Your application will be reviewed by admission committee. After your application has been reviewed we will contact you. If you have any questions before then, please contact the CREST office (858-534-9163 or [email protected] ).

For those who are interested in the Masters of Advanced Studies in Clinical Research degree after completing 20 units of CREST Curriculum, details can be found at http://clre.ucsd.edu .

Financial Matters: 

Important fee changes for summer-2024:.

In order to have access to course materials online through Canvas on time for class, you MUST submit your payment by due date.

For information about CREST Program payment, please contact Seble Chernet at [email protected] .

If interested in transferring to the degree program after completing 20 units with discounted fee through CREST Program, please visit the Masters Degree program website .

Program Format:

Broad-based curriculum encompassing major areas of clinical research that:

  • Can be completed in 1-3 years;
  • Given over one academic quarter each
  • Each course is designed to be given over one academic quarter and is comprised of 10 weekly, 2-hour periods of instruction which are given in the early evening (4-6). The regularly scheduled core classes are typically held from 4-6 pm on Wednesdays and Thursdays at UCSD La Jolla Campus.
  • Seminar series complement the modules and are given on Monday or Tuesday evenings from 4-7 Pm. Applicants are required to take one (2unit) seminar from Professional Development Series.  

In order to accommodate the varying needs, we have incorporated a track system which permits flexibility while retaining structured modular instruction.

  • Will involve a limited number of modules and is only for those who are interested in attending selected modules; can apply anytime but enrollment is based on space availability.
  •  Will commit to the entire eight module, two-year curriculum and will have receive course credit towards Masters degree in Clinical Research.
  • Taking all CREST modules is equivalent to approximately 20 credit units which can be applied towards a  Masters degree in Clinical Research . Track II enrollees are required to elect if they plan to apply these credits towards the MAS degree after completing 14-16 credit units in the CREST program.
  • Total units required for MAS degree: 40

Pace of Study:

Coursework can be completed in one to two years of study depending upon a participant's time to devote to the program. Students could enter the program either in the winter (January) or summer (July) quarter. *Please note that "Core Courses" are offered twice a year but you only need to take them once!

CLRE-251

2

X

 

X

 

CLRE-257

2

 

X

 

CLRE-250

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X

CLRE-256

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 X

 

 X

CLRE-253

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X

 

 

CLRE-254

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X

 

CLRE-252

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CLRE-255

2

 

 X

 

X

 

CLRE-259

 2

 X

 

 X

 

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CLRE-258

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 X

CLRE-258

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Current Students

Academic calendars/schedule of classes:, fy: 2023 - 2024, fy: 2024 - 2025, crest payment and registration:.

 SELF PAYMENT Istruction

Class Locations:

Click here for map & detailed ,   course website/canavs login:, : click here to redirect to login page, final grades and payment receipts:, click here to access system.




 

Contact CREST Office:
Email: [email protected]

Contact MAS Office:
Email: [email protected]

 CREST AND MAS ALUMNI

Our graduates are from a wide range of disciplines, and are diverse with respect to their level of training, primary degree, and background. 

 


   

What Alumni Have To Say About the Program:

Couldn’t have done it without crest!!!!!  Outstanding program, format and mentorship.  I wrote the first grant, but as i was only a fellow, the pi was my mentor.  I now feel poised to be my own pi on my own grant and am actively pursuing several avenues. 

Mimi Lukacz, MD, MAS

Great overview of clinical research - both investigator initiated and as part of collaborative studies.  This also gives clinical researchers an opportunity to meet investigators from different departments at UCSD, which allows future collaboration.  Overall a great learning experience. 

Thomas Savides, MD, MAS

This program has opened many doors for me.  The skills gained in grant writing, protocol writing, program management strategy, and outcomes identification have given me the unique opportunity to develop, implement, and evaluate new programs in the nursing department. 

Margaret B. (Scotti) Grant, RN,MAS

The CREST and Masters in Advanced Studies programs really gave me the tools to understand clinical research design and implementation.  During the program, I became Division Chief of Regional Anesthesia and Acute Pain Medicine at UCSD.  I founded the Regional Anesthesia and Acute Pain Medicine Fellowship and expanded the Division’s scope of patient care services and clinical research activities.  I was principal investigator or co-investigator on several single- and multi-center randomized clinical trials involving the innovative use of perineural local anesthetic infusions for postoperative pain control.  In 2010, I was offered and accepted a new position as Chief of the Anesthesiology and Perioperative Care Service at the VA Palo Alto Health Care System.  I am currently an Associate Professor of Anesthesia at Stanford University School of Medicine and the Co-Director of the Stanford Regional Anesthesia Fellowship Program.  I continue to run an active clinical research program focusing on the development of techniques and patient care pathways to improve postoperative pain control and other surgical outcomes. 

Edward Mariano, MD, MAS Associate Professor of Anesthesia at Stanford University School of Medicine and the Co-Director of the Stanford Regional Anesthesia Fellowship Program

In learning the basics and process of clinical research, I understand what is undertaken when I read the literature in my field of medicine. Also, I feel more powerful when deciphering study design and statistical analysis as it pertains to results/conclusions that are published. I am more able to evaluate which studies I should pay attention to and which to ignore. 

Anushirvan Minokadeh, MD, MAS

It has helped me become successful in my role in the medical device industry and has played a critical role in my career advancement. It has empowered me to be able to provide feedback in areas of Clinical Research and Post-market studies, to review abstracts/protocols etc and has sure prepared me for the real life experience. 

Khaudeja Bano, M.B.B.S, MAS Medical Director  Abbott Diagnostics Division

It gave me a foundation on clinical research, allowing me to have a solid training in clinical research methodologies, which is crucial as a clinical investigator. 

Jeffrey Lee, MD, MAS

CREST/MAS Program gave me excellent understanding of the Clinical Research process, including how to construct a protocol, understanding of regulatory requirements, bias, statistical assessments, etc. It has served me well in my medical affairs roles (mostly phase IV studies), and with my ability to assist with design and implementation of phase 3 studies. It has improved my ability to design and write meaningful clinical research. 

Ted Okerson, MD, FACP, MAS Senior Director, Global Medical Affairs, Allergan

I have not yet had a chance to start my own clinical research but I feel prepared in supervising the residents that I work with as well as moving toward starting my own research projects. 

Michelle Loose, MD, MAS

It gave me a thorough understanding of the basic terminologies, procedures, and sciences involved in conducting clinical research. 

Othman Mohammad, MD

An understanding of the different components of clinical research. The most valuable area was to meet senior researchers and to have those individuals mentor me in future projects. 

Adriana Tremoulet, MD, MAS

I am looking towards transferring from preclinical bench research to clinical research and this program has given me helpful insight into what monitoring a clinical trial entails. From budget and protocol preparation, to budget negotiation, data analysis techniques, data management and FDA audits, this program has given me a solid foundation from which to initiate a career in the clinical research arena. 

Christiane A Villescaz, MAS

The CREST program gave me a solid foundation for conducting patient-oriented clinical research and skills on describing the research methods and data analysis. These skills are crucial for me as I am getting ready for my first academic appointment. 

Milena Weinstein, MD,MAS

The Program helped me get a holistic view of the research process, an ability to analyze data using biostatistics, a greater ability to read and understand scientific papers, and time to pursue my own research endeavors. 

Alexander Ko, MD, MAS

The program gave me an introduction to the basics of research methodology. - Opportunity to network with senior faculty with successful academic careers -  Strengthened my interest in clinical research. 

Prasanthi Ramanujam, MD, MAS

Definitely gave me more confidence in my ability to design studies. Clarified many points for me. I’d taken courses on study design many years ago and this consolidated all the information. The very most useful one was Dr. Lindsay’s Epidemiology class. 

Ann Sturley, RN, MAS San Diego Hospice

The CREST Program gave me the capacity to better understand the major players in clinical and translational research and patient-centered studies; discuss the most recent advances and relevant statistical and methodological tools for effective and efficient design and conduct of clinical studies that are practice and community based; and to promote new avenues of investigation, the development of new approaches and techniques in translational and patient-centered research in my area of research interest which is nephrology. 

Rolando Claure Del Granado, MD, MAS Assistant Profesor in Nephrology at Universidad del Valle; Cochabamba–Bolivia

 ACTRI CREST 

Patient Oriented Research I & II,

    

Scientific Communication Courses 

 
  • Who can apply? 
  • If I am not with UCSD or UCSD affiliate, can I still apply to the program?
  • How do I apply to the program?
  • What are the admission requirements for CREST?
  • What are the admissions requirements for the MAS degree program?
  • When is the deadline for submitting the application?

Where do I send my application?

  • Could I register for the MAS degree program after completing the all the 2-year CREST courses?

How long does it take to complete the CREST program?

How many credit units are needed to earn the mas degree.

  • How much does it cost?

Who can apply?

Any doctoral candidates, postdoctoral fellows, or junior faculty who are pursuing a career in clinical or translational research can apply. Members of UCSD and its affiliates (UCSD staff, fellows, faculty, junior faculty, VA, Children's Hospital), apply through CREST.

If I am not with UCSD or a UCSD affiliate, can I still apply to the program?

Yes, you are eligible to apply through the Masters of Advanced Studies in Clinical Research degree program. Details of the Masters Degree program and fees can be found at http://clre.ucsd.edu/ .  

What are the admissions requirements for the CREST program?

Those interested in applying are encouraged to visit the CREST website , read and understand the descriptions and objectives of the courses they are interested in, review the course start and end dates, and review the overall program goals. For more information on admission, please visit the  Prospective Students page . Applicants must agree to commit to attending at least 70% of the classes for each course, and completing the majority of the homework. By the end of their first year in the CREST program, students must decide if they would like to apply for the MAS Program.

What are the admissions requirements for the Masters of Advanced Studies (MAS) in Clinical Research degree program?

Full- time UCSD Employee or Affiliate (employed by UCSD or affiliates like Rady Children’s Hosp., VA, etc) will apply through the CREST program (Track 2 – transferring to the MAS degree program after 20 units) and enjoy the discounted course fee instead of paying full MAS fee ($886/unit).  UCSD Fellows/Research Staff pay $340/unit and faculty pay $450/unit through CREST UP TO the first 20 units of the curriculum (40 total for the degree). The CREST and MAS curriculum are identical up to 20 units.

How do I apply?

UCSD and affiliates: UCSD fellows, faculty, junior faculty, VA, Children's Hospital should submit:

  • CREST Program Application
  • Agreement letter of primary supervisor (signed)
  • Resume or Curriculum vitae
  • Statement of Purpose 
  • Letters of Recommendation  (3)  

Non-UCSD affiliates: please visit  http://clre.ucsd.edu/  for detailed instructions on applying for the Masters of Advanced Studies in Clinical Research program.

UCSD and affiliates: Submit CREST Program Application  online. Required documents can be sent to: CREST Program Office University of California, San Diego 9500 Gilman Drive, Mail Code 0170X La Jolla, CA  92093-0170X [email protected]

Non-UCSD affiliates: See information at http://clre.ucsd.edu/ .

CREST program application deadlines

- The registration deadlines are September 30 for the January session and April 30 for the July session

Track II students:

  • Get Advanced Certificate in Clinical Research once completed the 20 unit
  • Continue for Master's Degree in Clinical Research

Track I students:

  • Enroll in individual courses
  • Enrollment is on a space available basis i.e. will be placed on a waiting list (first come-first serve) until administering the certificate/degree students.
  • Can't get Advanced Certificate in Clinical Research or continue for Master's Degree in Clinical Research.

If there are more applicants than can be accommodated for a given course, the Program Director and Co-Directors will determine which applicants will be accepted. Admission will be based on affiliation (preference given to UCSD/VA/Children's Hospital affiliates), level (preference given to fellows), expected benefit of the program to the individual (as determined by factors such as type of research and previous research experience), and date of submission of application.

Could I register for the MAS degree program after completing all of the entire 2-year CREST courses?

No,  you must decide by the end of your 1st year and/or prior to completing the 20 units (must enroll as Track II) if you are going to enroll in the degree program.

The CREST Program consists of 20 credit units of study. Coursework can be completed in 12 to 24 months of study, depending upon a participant's time to devote to the program. Students must enter the program in the winter (January) or in the summer (July) to complete the certificate program in 12 months.

The master's degree in Clinical Research consists of 40 credit units of study. Coursework can be completed in 18 to 30 months of study, depending upon a participant's time to devote to the program. Students enter the program in the winter (January)or in the summer (July) to complete the degree program in 18 months.

If I apply for the MAS degree program but then decide to leave after completing the second year, can I still receive a certificate for completing the CREST program?

Yes, you'll receive a certificate if you've completed the 20 credit units of study and passed the comprehensive exam.

How much does CREST cost?

All UCSD residents, fellows (including laboratory-based fellows), and faculty pay a discounted fee: The fee for UCSD residents and fellows is $680 per 2 unit course ($340/unit). The fee for UCSD faculty is $900 per 2 unit course ($450/unit). The fee for   Non-UCSD affiliates is $1,772 per 2 unit course ($886/unit)  The fee covers the costs for all lectures and course materials and books.

For those who are interested in the Master of Advanced Studies in Clinical Research degree, there will be additional university fees for each quarter of enrollment. Details of the Masters Degree program and fees can be found here.

  • Curriculum and Course Descriptions

(RN) Registered Nurse - Pediatrics Research - 131874

Job description, #131874 (rn) registered nurse - pediatrics research.

This position is a limited position with the possibility of extension/career conversion.

Special Selection Applicants : Apply by 9/10/2024. Eligible Special Selection clients should contact their Disability Counselor for assistance.

Current UC San Diego Health CNA (NX) represented RN/NP applicants will be considered after the first 7 days of job posting. All additional applicants will be considered after 14 days of job posting, pending the status of the initial internal CNA (NX) represented applicant pool.

This position will work a hybrid schedule which includes a combination of working both onsite on Campus and remote.

DESCRIPTION

UC San Diego Health is a Magnet designated organization, which is a prestigious recognition that applies to only 10% of all U.S. hospitals. Magnet is the "gold standard" for nursing excellence and is based on strengths in five key areas, which include transformational leadership, structural empowerment, exemplary professional practice, new knowledge, innovation and improvements and empirical outcomes. UC San Diego Health has held its Magnet status since 2011.

The Department of Pediatrics is one of the largest departments within the School of Medicine with approximately 250 Faculty, 127 postdoctoral fellows (both MDs and PhDs) along with over 320 support staff (not including hospital staff). In addition, the Department has 68 clinical residents distributed across the Divisions. The missions of research, education and patient care are intertwined, and are integral to the goals of the department.

The Department manages a university-affiliated children's health system with the physicians and leadership of the University of California, San Diego (UCSD), Rady Children's Hospital, and Rady Children's Specialists of San Diego, a Medical Practice Foundation, unifying pediatric patient care, research, education and community service programs.

The Pediatric Immunization Advancement Laboratory focuses on maternal and infant vaccinations, optimizing vaccination strategies in the community setting, and improving vaccine immunity. Our global research evaluates infant immune development, responses to mucosal vaccination, and the influence of breast milk and gut microbes on immune responses. Research starts at the bed side, is taken to the bench, and then back to bed side and community. Our goal is to find strategies to improve vaccine effectiveness and protect vulnerable infants and children from infectious diseases worldwide.

Under general supervision, Research Nurse will be responsible for running COVID-19, Influenza, RSV and other vaccine research protocols. Responsibilities vary by study and may include screening potential study participants, providing informed consent, administering vaccine, following subjects in longitudinal study protocols for routine and illness visits, medical record review, having telephone contact with participants, blood draws, nasal or nasopharyngeal swabs, other specimen collection, physical exam, completing case report forms; research scheduling; interact with research team, the UCSD Human Subjects Protection Program, and study sponsors, and other research related entities as needed.

While not required, a cover letter is highly recommended when applying to this position.

MINIMUM QUALIFICATIONS

Possession of the legal requirements to practice as a Registered Nurse as determined by the California Board of Registered Nursing and six months of clinical experience.

BLS/CPR certification at time of hire with commitment to get BART within 6 months of hire date.

A minimum of two (2) years experience in pediatrics, preferably in emergency room, inpatient, NICU, or ICU setting.

Must have excellent phlebotomy, IV insertion skills with experience in pediatrics.

Experience and ability to accurately collect, record, transcribe, and synthesize clinical data.

Demonstrated experience providing a wide variety of patient care activities including patient assessment, triage, obtaining a detailed medical history and vital signs, explaining medical conditions and procedures, reviewing medications and providing health education to clients, and coordinating care with clinical medical staff.

Knowledge regarding the standard pre-test or pre-procedure instructions that patients should receive.

Knowledge of the name, abbreviation, and purpose of various diagnostic tests/procedures, including proper scheduling and completion of necessary requisitions and consents.

Demonstrated experience interacting positively, constructively, and effectively with staff, physicians, patients, and the general public.

Excellent organizational skills with the ability to effectively and efficiently coordinate clinical and data activities for the enrollment and retention of patients on clinical trials.

Experience maintaining patient confidentiality and communicating (verbally and written) with patients, staff, and physicians with professionalism, sensitivity, and discretion.

Proficient at word processing, spreadsheet, and E-mail with experience producing reports, profiles, correspondence, graphs, and spreadsheets to generate and track required data.

Experience working independently and prioritizing tasks to meet strict guidelines and deadlines.

Experience performing effectively under conditions of high workload and frequent interruptions.

Ability to draw blood, start IV lines, and administer vaccines via all routes.

Must have reliable transportation and willing to perform home visits.

PREFERRED QUALIFICATIONS

Demonstrated experience with clinical research activities and guidelines related to consent, ethical conduct and protection of human subjects.

Demonstrated experience in operation and coordination of clinical trials or studies.

Experience reading and interpreting clinical research protocols and research policies and procedures.

Experience in providing care to a broad range patients.

Knowledge of and ability to communicate and ensure compliance of current UCSD Medical Center and Research policies and procedures. Knowledge of UCSD Medical Center, JCAHO, and Title XXII hospital licensing regulations.

Intermediate skills in using quality assessment and quality improvement methods.

SPECIAL CONDITIONS

Employment is subject to a criminal background check and pre-employment physical.

Must be willing to work a flexible schedule including occasional early mornings, evenings, and weekends.

Current State of California Registered Nurse (RN) license.

Pay Transparency Act

Annual Full Pay Range: $123,902 - $173,659 (will be prorated if the appointment percentage is less than 100%)

Hourly Equivalent: $59.34 - $83.17

Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).

If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements. If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community .

UC San Diego is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

For the University of California’s Affirmative Action Policy please visit: https://policy.ucop.edu/doc/4010393/PPSM-20 For the University of California’s Anti-Discrimination Policy, please visit: https://policy.ucop.edu/doc/1001004/Anti-Discrimination

UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.

UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.

Application Instructions

Please click on the link below to apply for this position. A new window will open and direct you to apply at our corporate careers page. We look forward to hearing from you!

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Posted : 8/27/2024

Job Reference # : 131874

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Borderzone Breakthrough: A New Source of Cardiac Inflammation

Published Date

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Ischemic heart disease is the most common cause of death in the world. It begins with a “heart attack”, also known as a myocardial infarction (MI), which causes part of the heart to die due to inadequate coronary blood flow. This leads to vigorous inflammation, heart wall remodeling, and heart failure.

Anti-inflammatory drugs have been surprisingly ineffective at preventing heart failure. As a consequence, they are not a routine part of post-MI care. However, it is possible that the most potent molecular and cellular inflammation targets have yet to be discovered.

In the Aug. 28, 2024 issue of Nature, researchers from University of California San Diego in the laboratory of Dr. Kevin King, associate professor of bioengineering and medicine, and a cardiologist at the Sulpizio Cardiovascular Center, report the discovery of a novel mechanism of cardiac inflammation that may expand therapeutic opportunities to prevent heart attacks from becoming heart failure.

Inflammation after MI is classically credited to professional immune cells like neutrophils and macrophages that infiltrate the infarcted heart and respond to molecules in the debris of dying cells. So the team was surprised when they discovered that the proinflammatory “type I interferon (IFN) response” was activated, not in the infarct where immune cells were concentrated, but instead in the borderzone, surrounding the infarct.

The borderzone has been a fascinating yet understudied area of the infarcted heart. It is where surviving heart muscle cells attempt to stabilize and even proliferate after being disconnected from their dying neighbor cells. Unfortunately, the borderzone has proven a challenging region to study because it is not easily isolated from the rest of the heart. Researchers overcame this obstacle using methods they recently reported based on single cell RNAseq and spatial transcriptomics where cells of the borderzone are recognized based on their patterns of gene expression ( https://www.nature.com/articles/s44161-022-00160-3 ).

To determine which cell type initiates borderzone inflammation, the team created a library of conditional knockout mice, each unable to initiate IFN signaling in a different cell type. To their surprise, heart muscle cells called cardiomyocytes emerged as the dominant initiators of borderzone IFN signaling. They found that mechanically stressed cardiomyocytes in the borderzone frequently suffered nuclear envelope rupture, which allowed escape of nuclear DNA and sensing by cytosolic DNA sensors, leading to activation of IFN signaling. This in turn caused mechanical weakening of the heart wall and made it vulnerable to dilation, thinning, and rupture, providing a mechanistic explanation for the team’s previous reported observation that mice lacking IFN responses exhibited improved survival after MI ( https://www.nature.com/articles/nm.4428 ).

“In the hospital, we care for patients with heart attacks and heart failure every day. New therapeutic targets for MI with the potential to prevent development of heart failure are incredibly important, said Dr. King, senior author of the study an on the faculty in the Shu Chien Gene Lay Department of Bioengineering and the Division of Cardiology at UC San Diego.

Many questions remain, however the newly reported findings suggest that limiting mechanical stress at the borderzone, inhibiting DNA sensing, and preventing type I IFN signaling may represent new opportunities for patients to avoid development of heart failure after MI.

Funding support for the study came, in part, from the NIH DP2 New Innovator Award.

Nature paper:  Spatially clustered type I interferon responses at injury borderzones

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Northwestern receives $55 million to advance health research

Largest active grant at Northwestern to fund clinical, translational research hub

Media Information

  • Embargo date: August 29, 2024 10:00 AM CT
  • Release Date: August 29, 2024

Media Contacts

Kristin Samuelson

  • (847) 491-4888
  • Email Kristin
  • Funding will enable discoveries for diverse populations to go from lab to clinical care settings
  • Will translate scientific research to treatments, therapies that can improve patients’ quality of life
  • Institute will infuse implementation-science methods into research to make public health improvements more scalable
  • ‘Clinical and translational research does not happen in a bubble’

CHICAGO --- The Northwestern University Clinical and Translational Sciences ( NUCATS ) Institute has received $55 million in National Institutes of Health (NIH) funding to accelerate the development, evaluation and implementation of improved health care interventions.

The seven-year award is the largest current research grant at Northwestern and extends a legacy of NIH funding that began when the institute launched in 2008.

The NUCATS Institute helps translate novel discoveries from the laboratory to routine clinical care, leading to treatments and therapies that can extend and improve the quality of life for patients. This is a process that remains slow, complex and labor intensive. NUCATS provides scientists at its four health system partners (Northwestern; Ann and Robert H. Lurie Children's Hospital of Chicago and its Stanley Manne Children’s Research Institute; Shirley Ryan AbilityLab; and Northwestern Medicine) with consultative resources and expertise to accelerate how quickly transformative scientific discoveries reach patients and communities.

“Clinical and translational research does not happen in a bubble. It requires dedicated investigators and members of the public to advance human health,” said Dr. Richard D’Aquila , associate vice president of research and senior associate dean for clinical and translational research at Northwestern University Feinberg School of Medicine. “With generous support from the NIH and Northwestern, we will continue to work alongside our exceptional coalition of community and health system partners to help build a better framework for innovating and implementing discoveries in ever more inclusive ways.”

NUCATS is led by principal investigators D’Aquila; Sara Becker , the Alice Hamilton Professor of Psychiatry; and Dr. Clyde Yancy , chief of cardiology at Feinberg.

“The collection of extraordinary faculty and staff who will manage this iteration of NUCATS is a testament to the transformational mindsets held by the institute’s leadership,” said  Dr. Eric G. Neilson , vice president for medical affairs and Lewis Landsberg Dean of Feinberg. “This funding allows us to further advance our mission to improve human health by investigating the mechanisms that drive the translation of discoveries toward real-world treatments.”

NUCATS and the multiple-principal investigator team will develop, evaluate and disseminate more effective health interventions to more patients more quickly following these three specific aims:

  • Include: Cultivate a culture of inclusive excellence as they expand their workforce, partnerships and research participants, including those historically underrepresented in biomedical science, to optimize the benefits of translation for all;
  • Innovate: Support innovation to accelerate and transform translation; and
  • Implement: Infuse implementation-science methods into clinical research.

The grant is awarded by the NIH's Clinical and Translational Science Awards (CTSA) Program , which supports a national network of medical institutions that speed the translation of research discoveries into improved care. The institute also is positioned to infuse implementation-science methods into work across the translational continuum to improve public health and meet the needs of all.

“Implementation science can help us accelerate and catalyze the uptake of evidence-based practice into routine clinical care,” said Becker, director of Northwestern’s Center for Dissemination and Implementation Science. “Northwestern is a national leader in this space. The NUCATS Institute will become a model CTSA hub that advances inclusive, innovative and implementable solutions to the evolving challenges that impede scalable public health progress.”

Yancy’s research in cardiology and health disparities addresses optimal treatment of heart failure. In a seminal contribution, he revealed the predominant cause of heart failure among Black people is hypertension rather than the ischemic heart disease, which is most often the commonly accepted cause in non-Black patients. His groundbreaking work informed how to optimize treatment strategies for Black patients, including the first-ever FDA-approved therapy specifically for Black patients.

“Diversity in the biomedical workforce is more than representativeness, it is rather about excellence, diverse ideas and unique strategies that will enrich our ability to provide care for the entire population,” said Yancy, vice dean for diversity and inclusion at Feinberg. “By addressing inequities with intentionality, we are positioned to understand and then overcome persistent systemic limitations that hurt those underrepresented and underserved populations and, in turn, impair best health for everyone. We commit to responsibly and courageously leading the path to inclusive excellence and belonging.”

Since launching in 2008, the NUCATS has supported more than 3,500 academic publications and annually facilitates more than $1 million in competitive pilot research projects that seed new NIH applications.

The new CTSA activities are funded by the National Center for Advancing Translational Sciences (grant UM1TR005121) , which is part of the NIH.

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clinical research masters ucsd

Samantha Hurst , PhD

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COMMENTS

  1. Home

    Home - UCSD Master's in Clinical Research. WHY WAIT? ADVANCE YOUR CAREER WITH A. MASTER'S IN CLINICAL RESEARCH. Learn More. Applications will open September 4, 2024. Deadline to submit is January 15, 2025. All students are required to start in June (i.e. Summer Quarter) Learn More.

  2. Program Overview

    The master's degree in Clinical Research helps students meet the demand for well-qualified clinical researchers in academia and industry. This critical need for individuals who are able to conduct credible patient-based research within stringent ethical and regulatory guidelines continues to grow. Current estimates point to the need for more ...

  3. Curriculum

    The masters in Clinical Research curriculum is designed to educate and train clinical researchers to conduct credible patient-based research within stringent ethical and regulatory guidelines in academia and industry. Taught by the internationally highly ranked faculty of UC San Diego's School of Medicine and experts in the health sciences.

  4. Clinical Research

    Clinical Research [ courses | faculty] The Campus on Villa La Jolla 8950 Villa La Jolla Drive, Suite A-212 (858) ... The UC San Diego Graduate Division confers the MAS and the Department of Medicine in the UC San Diego School of Medicine is responsible for the academic management of the curriculum. UC San Diego Extended Studies and Public ...

  5. Degree Programs

    Division of Graduate Education and Postdoctoral Affairs Graduate Division UC San Diego. Search. Search Term. Close Nav. About . Our Impact; Meet the Dean; Meet the Team ... Clinical Research; Drug Development and Product Management; ... UC San Diego 9500 Gilman Dr. La Jolla, CA 92093 ...

  6. Application & Requirements

    Please complete an online application: submit a minimum TOEFL score of 85 or 7.0 on the IELTS. CREST students: You may matriculate into the Clinical Research masters program during other quarters. Contact [email protected] for more information. Please note, CREST Applications have to be completed through a separate portal.

  7. Clinical Research

    Clinical Research [ program | courses] All courses, faculty listings, and curricular and degree requirements described herein are subject to change or deletion without notice. ... CPH, FRSPH, Academic Coordinator, UC San Diego Extension. Colin Depp, PhD, Associate Professor, Department of Psychiatry. Jennifer J. Ford, ... (858) 534-2230 ...

  8. Clinical Trials at UCSD

    Search Trials. explore 1180 studies at UCSD, including Pain, HIV/AIDS, and more. Click to see a list of 108 Carcinoma clinical trials at UCSD. Click to see a list of 77 Lung Cancer clinical trials at UCSD. Click to see a list of 67 Solid Tumor clinical trials at UCSD. Click to see a list of 68 Non-Small Cell Lung Cancer clinical trials at UCSD.

  9. About Us

    CREST Program Representative - Department of Medicine / ACTRI, UC San Diego. Graduate Student Program Advisor & Coordinator - MAS in Clinical Research, Office of Advanced Professional Education and Development, UC San Diego Extended Studies. Director - Clinical Services Lilly Biotechnology Center, Eli Lilly & Co.

  10. Clinical Research Enhancement through Supplemental Training (CREST) Program

    Track II scholars have the option to enroll in the UCSD Masters of Advanced Studies in Clinical Research anytime during the first year of training and can apply the CREST curriculum credits towards the Masters degree. ... The master's degree in Clinical Research consists of 40 credit units of study. Coursework can be completed in 18 to 30 ...

  11. (RN) Registered Nurse

    The Department manages a university-affiliated children's health system with the physicians and leadership of the University of California, San Diego (UCSD), Rady Children's Hospital, and Rady Children's Specialists of San Diego, a Medical Practice Foundation, unifying pediatric patient care, research, education and community service programs.

  12. Clinical Research

    Clinical Research [ courses | faculty] The Campus on Villa La Jolla 8950 Villa La Jolla Drive, Suite A-212 (858) 534-9164 Email: [email protected] ... Individuals should submit and complete the official UC San Diego online graduate application for admission, the application fee, one set of official transcripts from each institution attended after ...

  13. At the Ready: A Day in the Life of a Trauma Surgeon

    Approximately 3,000 patients are cared for in the Trauma Center at UC San Diego Health each year. In 1984, UC San Diego Health was instrumental in positioning the San Diego Trauma System, as the standard of trauma care. The system was a first of its kind in the nation and is made up of six designated trauma centers, encompassing UC San Diego ...

  14. Prospective Students

    Raphael Cuomo, PhD, MPH, CHP, FRPH. Are you a working professional in the early to mid-stage career seeking to go the next level? We offer. Flexible Schedule. Interactive classroom environment with peers and faculty. Broad-based curriculum. Integrative, high-level clinical research project.

  15. Borderzone Breakthrough: A New Source of Cardiac Inflammation

    In the Aug. 28, 2024 issue of Nature, researchers from University of California San Diego in the laboratory of Dr. Kevin King, associate professor of bioengineering and medicine, and a cardiologist at the Sulpizio Cardiovascular Center, report the discovery of a novel mechanism of cardiac inflammation that may expand therapeutic opportunities to prevent heart attacks from becoming heart failure.

  16. Resources

    The success of the Clinical Research master's degree is possible through its many partnerships and UC San Diego resources. This is a Master of Advanced Studies (MAS) degree conferred by the Graduate Division at UC San Diego. The MAS degrees are self-funded and receive no state funded support. The Western Association of Schools and Colleges ...

  17. Northwestern receives $55 million to advance health research

    The Northwestern University Clinical and Translational Sciences (NUCATS) Institute has received $55 million in National Institutes of Health (NIH) funding to accelerate the development, evaluation and implementation of improved health care interventions. ... Largest active grant at Northwestern to fund clinical, translational research hub. Skip ...

  18. Bachelor's to Master's at UCSD

    Advance your career with a Master's in Clinical Research Ideal for students who have recently finished undergraduate programs, are current medical students on a gap year, students with pharmaceutical research backgrounds, or medical residents/fellows.

  19. FAQ

    The master's degree in Clinical Research is a degree designed to supplement one's training, education and experience. At present, formal training in clinical research methodology is limited and typically not a requirement of traditional graduate study for healthcare professionals. As a result, most academic scientists, as well as ...

  20. Faculties Archive

    Jennifer J. Ford, MBA, has spent her research administration career at University of California, San Diego (UC San Diego) an academic medical center since 2000. ... Dr. Graves is the Online Course and Program Development Director for the UC San Diego MAS in Clinical Research/CREST Program and a faculty instructor for the in-residence Patient ...

  21. Financial Details

    A 2019 survey revealed that Clinical Research Managers and Clinical Data Managers with a master's degree earned a mean salary of $97,000. The cost of the Clinical Research master's degree program is approximately $36,000, which includes all program instruction and administrative fees. Program fees do not include books for elective courses ...

  22. Featured Alumni

    2016 MAS, Clinical Research, University of California, San Diego; ... "The MAS program at UC San Diego provided me with a unique opportunity to comprehensively study clinical research methodology and protocol while simultaneously allowing me to conduct clinical research. Such a balance allowed me to directly implement what I learned in the ...

  23. Information Session

    Information Sessions Are a Great Way to Learn More About Our Program. During this Live Online Webinar, you will meet our faculty, your graduate advisor, and other prospective students. Additionally, you can also meet current students or alumni who can provide a first-person perspective about what it is like to be a student in the program.

  24. Clinical Research Symposium

    Second Annual Clinical Research Symposium. The second annual Clinical Research Symposium was conducted on the virtual platform VirBela showcasing our MAS students' Independent Study Projects. View the top four presentations from our 2021 class below.

  25. Lecture Preview

    Online Form - CLRE Lecture Preview

  26. Siddharth Singh

    Siddharth Singh, MD. Siddharth Singh. Course Director- CER/Comparative Effectiveness Research. Assistant Professor - Clinical Medicine, Division of Gastroenterology, Department of Medicine, UC San Diego School of Medicine.

  27. Samantha Hurst

    Samantha Hurst, PhD. Course Director - Qualitative Research, Project Scientist, Department of Family Medicine and Public Health, UC San Diego School of Medicine.