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Mmri is an independent, nonprofit medical research institute located in the heart of silicon valley, in sunnyvale, ca. research at mmri focuses on understanding the molecular basis of chronic disease and identifying potential therapeutic intervention points in cancer, inflammation, and autoimmune diseases. mmri drives scientific discovery at the bench with the goal of facilitating the translation of these discoveries into solutions for important disease problems..
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Positive Allosteric Modulation of A2AR Alters Immune Cell Responses and Ameliorates Psoriasis-Like Dermatitis in Mice. Welihinda AA, Ravikumar P, Kaur M, Mechanic J, Yadav S, Kang GJ, Amento EP. PMID: 34536482
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Medical Research Institute Sri Lanka
The national reference laboratory and the premier medical research institute in sri lanka, medical research institute - sri lanka.
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The mission at Academic Medical Research Institute is to continuously test means of improving management of disease, and quality of life of patients.
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Yekaterinburg , city and administrative center of Sverdlovsk oblast (region), west-central Russia . The city lies along the Iset River, which is a tributary of the Tobol River , and on the eastern slope of the Ural Mountains , slightly east of the border between Europe and Asia . Yekaterinburg is situated 1,036 miles (1,667 km) east of Moscow .
Near the village of Shartash, which was founded in 1672 by members of the Russian sect of Old Believers, an ironworks was established in 1721 and a fortress in 1722. In 1723 the new settlement was named Yekaterinburg in honor of Catherine I , the wife of Peter I the Great . The town grew as the administrative center for all the ironworks of the Urals region, and its importance increased after 1783, when the Great Siberian Highway was built through it. After 1878 the Trans-Siberian Railroad linked the city with Siberia. After the Russian Revolution of 1917 (October), Yekaterinburg achieved notoriety as the scene of the execution of the last tsar , Nicholas II , and his family in July 1918. In 1924 it was renamed Sverdlovsk in honor of the Bolshevik leader Yakov M. Sverdlov, but the city reverted to its original name in 1991.
Modern Yekaterinburg is one of the major industrial centers of Russia, especially for heavy engineering. The Uralmash produces heavy machinery and is the city’s largest enterprise; it once employed some 50,000 workers, though it now has a small fraction of that number. Engineering products manufactured in the city include metallurgical and chemical machinery, turbines, diesels, and ball bearings . During the Soviet period the city was a major center of biological and chemical warfare research and development . There is a range of light industries, including a traditional one of gem cutting. Food processing is also important. The city, laid out on a regular gridiron pattern, sprawls across the valley of the Iset—there dammed to form a series of small lakes—and the low surrounding hills.
Yekaterinburg is an important railway junction, with lines radiating from it to all parts of the Urals and the rest of Russia. The city is the leading cultural center of the Urals and has numerous institutions of higher education , including the Urals A.M. Gorky State University (founded 1920), a conservatory, and polytechnic, mining, forestry, agricultural, law, medical, and teacher-training institutes. The Urals branch of the Russian Academy of Sciences and many scientific-research establishments are also located there. Boris Yeltsin , the first democratically elected president of Russia, was educated and spent much of his political career in the city. Pop. (2005 est.) 1,304,251.
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Cancer mortality in chrysotile miners and millers, Russian Federation: main results (Asbest Chrysotile Cohort Study)
An international research group of scientists from the International Agency for Research on Cancer (IARC), the Izmerov Research Institute of Occupational Health (IRIOH) in Moscow (Russian Federation), the Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers (Russian Federation), and the Institute for Risk Assessment Sciences, Utrecht University (The Netherlands) reports the main results on cancer mortality from a historical cohort study of workers employed in the world’s largest chrysotile (asbestos) mine and its enrichment factories located in the town of Asbest, Sverdlovsk Oblast, Russian Federation. These results were published today in the Journal of the National Cancer Institute .
The study was based on company employment records of all workers who had, after 1975, worked for at least 1 year in any enterprise of the mine or its factories; all of those enterprises had systematic stationary dust measurement surveillance. The cohort includes 30 445 workers (32% women), of whom 54% had worked for more than 30 years in the mine or enrichment factories. Cohort members were followed up for vital status and cause of death until 2015.
Mesothelioma mortality was strongly increased with higher cumulative exposure levels, based on 13 deaths from this cause overall; none of those deaths occurred among workers in the lowest exposure category. There was increasing mortality from lung cancer in men with increasing cumulative exposure, with a 40% higher risk of dying from lung cancer in the highest percentile of cumulative exposure. In women, based on much smaller numbers of deaths from lung cancer, the association was less strong. Inconsistent associations were seen between cumulative exposure and mortality from colorectal cancer and stomach cancer. No increased mortality was seen for laryngeal cancer or ovarian cancer.
The study confirms that exposure to dust containing chrysotile mined in the world’s largest active asbestos mine increases the risk of developing cancer in a dose-dependent manner. This was confirmed for mesothelioma and for lung cancer. For lung cancer, it suggests an interplay with other lung carcinogens, especially tobacco smoking, and perhaps also with other occupational exposures, which may be why the increased risk was clearer in men and at lower exposure levels than in women.
The unique feature of the study is the reconstruction of past exposures to dust for every individual worker, by linking the wealth of information of almost 100 000 dust measurements carried out over more than six decades with the detailed occupational history of workers from their employment records of when and exactly where each worker worked in the mine or factories. Also, based on parallel dust and fibre measurements, cumulative exposure to chrysotile fibres could be estimated. Access to the original death certificates enabled a unified classification of causes of death according to international guidelines using the most up-to-date medical classification of disease. Limitations are inherent in the epidemiological study design of an archive-based approach with no personal contact with workers.
Schüz J, Kovalevskiy E, Olsson A, Moissonnier M, Ostroumova E, Ferro G, et al. Cancer mortality in chrysotile miners and millers, Russian Federation: main results (Asbest Chrysotile Cohort Study) J Natl Cancer Inst , Published online 22 January 2024; https://doi.org/10.1093/jnci/djad262
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Published in section: IARC News
Publication date: 22 January, 2024, 0:52
Direct link: https://www.iarc.who.int/news-events/cancer-mortality-in-chrysotile-miners-and-millers-russian-federation-main-results-asbest-chrysotile-cohort-study/
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Subscribe to our newsletter and receive our news in your inbox. Mailing Address: Masonic Medical Research Institute 2150 Bleecker Street Utica, NY 13501 Telephone & Fax Telephone: 1-315-735-2217 Toll-Free: 1-888-888-6675 FAX: 1-315-735-5648 Web Contact Form Directions to MMRI Speakers And Tours Please use the online contact form above to ...
Research Priorities Gates MRI focuses on programs aimed at reducing the burden of tuberculosis (TB), malaria, diarrheal diseases, and maternal, newborn, and child illnesses in low-and-middle-income countries (LMICs). About Us The Bill & Melinda Gates Medical Research Institute is a non-profit organization dedicated to the development and effective use of novel biomedical interventions ...
The Bill & Melinda Gates Medical Research Institute is a non-profit organization dedicated to the development and effective use of novel biomedical interventions addressing substantial global health concerns, for which investment incentives are limited. The institute works through collaborating partners and organizations, coordinating and ...
Main Contact. phone: 301-571-0760; Fax: 301-571-0769; email: [email protected] ... E. Fuller Torrey, M.D. Associate Director of Research; email: [email protected]; John Davis, M.D. Associate Director for Treatment Trials; University of Illinois at Chicago Department of Psychiatry-CS 1601 W. Taylor St., P1 324W, MC912 ...
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The Sverdlovsk Medical Institute was founded on March 1, 1931, on the basis of a special ... a number of Jewish doctors were dismissed at the Sverdlovsk Medical Institute (as well as from medical institutions in the city). ... the Central Scientific Research Laboratory was formed as part of eight laboratories; In 1969 - the 3rd educational ...
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The premier medical research institute in Sri Lanka. Medical Research Institute - Sri Lanka ... For bookings please contact Mr Ajith Ranathunga 0112693532-34, 0112693527, Mobile: 0779421346 Booking application form can be collected at Director's office MRI or click here.
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The mission at Academic Medical Research Institute is to continuously test means of improving management of disease, and quality of life of patients. Academic Medical Research Institute (AMRI) has been conducting clinical trials in Los Angeles, California since 2007. Our stellar team of clinical research coordinators and assistants aspire to ...
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The number of doctors in public medical institutions is 11,339 people (83.9 per 10,000 people) and the number of nurses is 16,795 (124 per 10,000 people). Private medical institutions also operate in the city. [147] Main building of the Ural Federal University
Contact MIR - Medical International Research USA, Inc. for more information on our innovative professional and personal spirometers. ... MIR - Medical International Research USA, Inc. 5462 S. Westridge Drive New Berlin, WI 53151 USA. Email: [email protected]. Phone: +01 (262) 565-6797 +01 (262) 364-2030
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Yekaterinburg is situated 1,036 miles (1,667 km) east of Moscow. Yekaterinburg, Russia. Near the village of Shartash, which was founded in 1672 by members of the Russian sect of Old Believers, an ironworks was established in 1721 and a fortress in 1722. In 1723 the new settlement was named Yekaterinburg in honor of Catherine I, the wife of ...
Cancer mortality in chrysotile miners and millers, Russian Federation: main results (Asbest Chrysotile Cohort Study) An international research group of scientists from the International Agency for Research on Cancer (IARC), the Izmerov Research Institute of Occupational Health (IRIOH) in Moscow (Russian Federation), the Yekaterinburg Medical Research Center for Prophylaxis and Health ...